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460,000 people, 19 years: “ultra-processed” isn't the whole story for bowel cancer

A huge US study found no link between how much ultra-processed food people ate overall and bowel cancer. Before you grab the crisps: what's inside the package still matters a lot.

1 min read
Sausages hanging from hooks

“Ultra-processed” has become the scary word of the decade. Cereals, sliced bread, flavoured yoghurt, ready meals, all thrown in one bag. Now a giant study says the bag might be too big.

The study

Scientists at the US National Cancer Institute looked at 461,682 Americans aged 50 to 71, who joined a diet study in 1995 or 1996. They followed them for a median of almost 19 years. That's a lot of breakfasts.

The result, published in PLOS Medicine on 15 October: total ultra-processed food was not linked to colorectal, or bowel, cancer overall. As the lead researcher Erikka Loftfield put it: “we did not observe an association between total ultra-processed food (UPF) intake and colorectal cancer incidence”.

Cartoon: a happy wholegrain cereal box and a nervous sausage under a magnifying glass

The plot twist

Look inside the bag and things change. Ultra-processed foods with whole grains, fibre, dairy and calcium were linked to a lower bowel cancer risk. Processed meat was linked to a higher one. Swapping 10% of ultra-processed food for minimally processed food was linked to about 2% lower risk.

So a wholegrain cereal and a hot dog are both “ultra-processed”, but they don't act the same in this study. Your gut could have told you that.

Read the small print

Most people in the study were older white Americans, so the results may not fit everyone. Their diet was asked about only once, at the start, and a lot changed in 20 years. It's an observational study, so it shows links, not proof. And it's only about bowel cancer, not your heart or your waistline.

In the US, ultra-processed foods make up more than half of what adults eat. So the useful question isn't “is it processed?” but “what's in it?”

Practical tip: next time you shop, flip the box and look for “whole grain” and fibre. And maybe leave the salami for Sundays.

Sources
  1. ScienceDaily, “Massive study of 460,000 people challenges ultra-processed food cancer fears”, Oct 2026 (National Cancer Institute, PLOS Medicine)
  2. ecancer, “Total ultra-processed food intake not linked to colorectal cancer in large US cohort study”, 16 Oct 2026
  3. Abar L., Loftfield E. et al., “Ultra-processed food intake and colorectal cancer risk in the NIH-AARP Diet and Health Study”, medRxiv preprint

Photo: Danielle Suijkerbuijk / Unsplash · Unsplash License · Illustration made with AI

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